tl;dr: Discovery Loop is a new startup founded by Jeff Dean, Sanjay Ghemawat, Quoc Le, and Oriol Vinyals aimed at automating the scientific experimental loop using frontier AI models and large-scale compute. The company will initially focus on automating machine learning research itself, then expand to tackle NAE Grand Challenges like drug discovery, solar energy, and clean water. They're building a lean, in-person team leveraging full-stack expertise from chips to models.