The worthlessness of Vitamin D is mildly exaggerated(dynomight.net)
312 points by surprisetalk 19 hours ago | 227 comments
tl;dr: Vitamin D RCTs have refuted the magical correlations (no 30% mortality reduction), but the author argues skeptics overcorrected: trials consistently show hazard ratios slightly below 1 for cancer and all-cause mortality, and detecting modest-but-meaningful effects would require sample sizes far larger than any trial conducted. Combined with evolutionary evidence (ancestral levels ~115 nmol/L, pale skin evolving despite folate costs) and biology (vitamin D receptors throughout the body), supplementing if you have low-ish levels is probably worthwhile—even a HR of 0.96 would beat the cost of a daily pill.
HN Discussion:
  • ~Sunlight itself, not just vitamin D, drives health benefits through multiple pathways
  • Personal anecdotes confirming vitamin D supplementation reduces illness
  • ~Vitamin D deficiency claims are overhyped by supplement industry and influencers
  • Methodological concerns about studies—dosing, K2 cofactor, blood level measurement
  • Blood vitamin D may just be a proxy for outdoor exercise, which is the real cause