tl;dr: A case report describes an octogenarian woman with 10-year advanced Alzheimer's who, after a 5g dose of psilocybin mushrooms, showed transient multidomain improvements including restored urinary continence, independent ambulation, autobiographical speech, and social engagement—gains persisting for weeks and reinforced by a second 3g session. The authors stress this isn't disease reversal but suggests residual functional capacity may remain accessible via neuromodulation; limitations include the single-case design, no biomarker confirmation, no standardized cognitive scales, and inability to rule out spontaneous fluctuation.